Natalee Holloway, an 18-year-old from Mountain Brook, Alabama, disappeared on May 30, 2005, while on a senior trip to Aruba. She was last seen leaving a nightclub with Joran van der Sloot and two others. Despite extensive searches and global media coverage, Natalee was never found. In 2012, she was legally declared dead. In 2023, van der Sloot finally admitted to killing her, bringing some closure to her family.